An All Natural Clinically Formulated Therapy

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According to sales data provided by Insight Health. The #1 Joint Health pill in Germany is a Systemic Multi Enzyme Therapy formulation. 


"The results obtained from six randomized controlled trials lasting 3–12 weeks demonstrated for both treatment groups comparable efficacy and clinically relevant improvement with respect to knee-joint pain and pain-related restrictions"


"Knee joint function and joint-associated pain quantified using the Lequesne Functional Index improved...

The relative reduction in total score was −27.4%"*


Subjects who received a Systemic Multi Enzyme Therapy formulation experienced improvement at day 7 and were able to return to work and/or training faster*


Systemic Enzyme Multi Therapy formulations “showed comparable efficacy and a superior tolerability/safety profile associated with a significantly lower risk of treatment-emergent adverse events”


A Systemic Multi Enzyme Therapy formulation demonstrated superiority in maintaining strength and muscle comfort in response to exhaustive eccentric exercise

What other users are saying

I am suffering from rheumatoid arthritis and I have been looking for alternative medicine to relieve the pain, stiffness and discomfort that I experience on a daily basis. I found this and started taking 6 tablets a day on an empty stomach. Two weeks later, I found it easier to get out of bed and less edema in my legs. I continued this and did a blood test. My CRP and ESR have dropped significantly

The day it arrived I took my first pills right after opening the package . I had been in the garden for hours, so I met the empty stomach requirement. Later that night I noticed that the pain in my right hand and wrist was gone! Before, the  arthritis pain was a constant, almost 24/7. 

Holy cow! This thing really works !!! I had mild arthritis and knee pain and didn't know what to do. .. After a month taking it, the pain is mostly gone! I was able to walk for a while. The rest of the joints also feel like 25 years younger! 

Diane t - Great for the pain

I suffer from both rheumatoid and osteoarthritis. I used to take Advil or Aleve because I'm allergic to all the pain medications that would normally be prescribed for my conditions. I have been using this particular product with amazing results, it controls the overall pain that comes from the arthritis.

Beth b - It really helped

Started using product on May 2020, and, believer or not, within one week  I was able to notice the knee arthritis pain subsiding and continuously decreasing, this product has helped a lot.

My mom has severe degenerative arthritis. She used to suffer from lots of pain, but we were concerned about the normal medications because of her blood pressure. Now she has been taking 12 of these a day and swears by them. She has not slowed down at all, she even went out for a walk twice.

You are fully protected by the 100% Risk Free Heal-n-Soothe Guarantee.

Your Free eBook!

As part of your Risk Free Heal-n-Soothe Bottle, you'll also get these digital products. All you have to do check your e-mail to claim this offer, and after using the Heal-n-Soothe Systemic Formula, tell us how it has helped you in your health journey.

- and , if you didn't sing up before, you can do it now, you can scroll down and let us know where to send you these digital products.

Joint Health 101


This is the ultimate guide for understanding the most common health dilemma that affected millions of people — joint problems.

Normally priced at normally priced at $9.99, but today, it can be yours  completely for Free after getting your FREE 90 count Bottle!

Share with your Friends

We spoke to the creators of this product and to be fair, we can only offer 1 FREE 90 count Bottle per user, but you can always go ahead and tell your friends so they can also get one from us.


1 Marzin T, Lorkowski G, Reule C, et al. BMJ Open Sport & Exercise Medicine 2017;2:e000191.

2 Ueberall MA, Mueller-Schwefe GH, Wigand R, et al. Journal of Pain Research 2016;9:941-961.

3 Bolten WW, Glade MJ, Raum S, et al. Arthritis 2015;doi:10.1155/2015/251521.

4 Kleine MW. Journal of Clinical Research 1998;1:87-102.

5 Baumuller M. Allgemeinmedizin 1990;19(4):178-182.

6 Leipner J, Iten F, Saller R. BioDrugs 2001;15(12):779-789.

7 Akhtar N, Naseer R, Farooqi A, Aziz W, Nazir M. Clinical Rheumatology 2004;23:410-5.

8 Klein G, Kullich W. Clinical Drug Investigations 2000;19:15-23.

9 Szczurko O, Cooley K, Mills EJ, Zhou Q, Perri D, Seely D. Arthritis & Rheumatology 2009;61(8):1037-1045.

10 Kameníček V, Holaň P, Franěk P. Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 2001;Ch-7.

11 Vinzenz K. Ödembehandlung bei zahnchirurgischen Eingriffen mit hydrolytischen Enzymen. Chirurgische Zahnheilkunde 1991;7:1053-1064.

12 Rahn HD. Praktische Sport-Traumatologie und Sportmedizin 1994;10(1):22-27.

13 Baumuller M. Allgemeinmedizin 1990;19(4):178-182.

14 Rahn HD. Deutsche Zeitschrift für Sportmedizin 1995;9:426-431.

15 Mazurov VI, Stolov SV, Linetskaya NE, Onyschenko EF. International Journal of Immunotherapy 2001;17(2/3/4):113-120.

16 Paradis M-E, Couture P, Gigleux I, et al. Pharma Nutrition 2015;3(3):85-88.

17 Koshkin VM, Kirienko AI, Leontjev SG, et al. Angiology and Vascular Surgery 2000;6(2):61-64.

18 Ueberall MA, Mueller-Schwefe GH, Wigand R, Essner U. Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials. J Pain Res. 2016;9:941-961. Published 2016 Nov 4. doi:10.2147/JPR.S108563

19 Wolf, M., & Ransberger, K. (1977). Enzyme therapy. Regent House.

20 Bolten, Wolfgang W et al. “The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial.” Arthritis vol. 2015 (2015): 251521. doi:10.1155/2015/251521

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The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

The information we provide is not intended to replace consultation with a qualified medical professional. We encourage you to inform your physician of changes you make to your lifestyle and discuss these with him or her. For questions or concerns about any medical conditions you may have, please contact your doctor.

Dr. Ana Alves is a pen name used for marketing purposes and to protect the author’s identity.  Any likeness to a real Ana Alves living or dead is entirely coincidental.